Virus implicated in the development of various cancers. How we can cure them?

There are at least 7 viruses implicated in the pathogenesis of 10% to 15% of all human cancers worldwide. Despite a high prevalence of infection with these viruses, only a minority of infected individuals develop a subsequent malignant tumor, underscoring the important role that host and environmental factors have in cancer development. Nowadays, is in the use of medical practice the use vaccine against human papilloma virus mainly for the prevention of cervical cancer and oral & neck cancers. The immune evasion mechanisms of these viral infections have an important role in carcinogenesis. Increased understanding of these mechanisms has paved the way for using immunotherapy to treat virus-associated cancers. Therefore, currently is being tested in clinical trials the use of adoptive cell therapy, tumor vaccines, immune checkpoint inhibitors, and combination immunotherapies in the treatment of select virus-associated cancers. Immunotherapy is proving to be a useful strategy in the treatment of virus-associated cancers. A greater understanding of the processes of immune evasion in chronic infections and malignant tumors will continue to help in the goal of optimizing immunotherapy, which will in turn translate into remission and long-term survival in this patient population.