Some aggressive ovarian cancers start in the fallopian tubes, not the ovaries
The most aggressive type of ovarian cancer develops from cells that come from the fallopian tubes rather than the ovaries, according to a small study.
The findings confirms growing scientific suspicion around the origins of the disease, and could lead to news ways to prevent and treat it.
There are 5 types of ovarian cancer, of which high-grade serous ovarian carcinoma (HGSOC) accounts for the majority of cases and is also the most aggressive. It is normally diagnosed late,
Until recently it was thought that the disease developed from cells lining the surface of the ovary, but studies have suggested it might start in the fallopian tubes instead.
And for the first time scientists have traced specific genetic faults from the start of the disease through to it spreading.making it difficult to treat.
“The study confirms that faults in the p53 gene really are the initiating mutation in this disease."
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