UP TO DATE INFORMATION AND NEWS RELATED TO CANCER RESEARCH AND TREATMENT FOR CANCER PATIENTS AND COMMUNITY.
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Friday, 9 February 2018
Thursday, 8 February 2018
Thursday, 1 February 2018
Women who get breast implants may be more likely to develop anaplastic large-cell lymphoma, a small Dutch study suggests.
Anaplastic large-cell lymphoma is an aggressive form of non-Hodgkin lymphoma, which typically affects older adults and is more common in men than in women. In recent years, the number of women diagnosed with anaplastic large-cell lymphoma in the breast has increased, raising concerns that implants might cause malignancies, researchers note in JAMA Oncology.
For the current study, researchers examined data on patients with non-Hodgkin lymphoma of the breast who were added to a Dutch cancer registry between 1990 and 2016. Among 43 patients with breast anaplastic large-cell lymphoma, 32 had breast implants, compared with just one woman among the 146 patients in the study who had other types of breast lymphomas.
This suggests that women with breast implants are 421 times more likely to develop breast anaplastic large-cell lymphoma. But the absolute risk is low: by age 75, only one in every 6,920 women with implants will develop this type of cancer.
Therefore, “Women who have implants should be aware of the signs and symptoms
so that they can consult their doctors in time when they notice enlargement of
the breast or a lump” In particular, so-called macrotextured implants may pose
a bigger risk.
Wednesday, 31 January 2018
The Challenging Landscape of Cancer and Aging: Charting a Way Forward
Thanks to improvements in health care, life expectancy in
both the United States and globally is substantially longer now than it was 50
years ago.
In 2010, more than 40 million people in the United
States, or 13% of the population, were older than age 65. This demographic, the
fastest-growing segment of the population, will more than double to nearly 84
million, or more than 20% of the population, by 2050.
The convergence of an overall aging population and a peak
cancer incidence among those aged 65 to 74 will result in a significant rise in
the number of people diagnosed with cancer. Cancer also occurs at a high rate
in people older than 75, but at that age people are more likely to die from
other medical conditions.)
Age is a well-recognized risk factor for cancer
development. In fact, you could say aging is the major carcinogen. The
normal aging process affects many important biological processes within our
bodies that result in the deterioration of proteins and DNA in cells. Many of
these damaged cells enter a state of arrested growth, called “senescence”—no
longer dividing and growing, but still remaining metabolically active and
capable of causing problems. Senescence is an efficient protective mechanism
against cancer, forcing would-be cancer cells to stop dividing. But the
senescence mechanism sometimes fails, and accumulating cancer-causing mutations
produce the uncontrollable cell growth that—with a supportive microenvironment—causes
the formation and spread of cancer.
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